What moved in your trials overnight.
Pick a sponsor or disease. Every morning DataLookout compares each of their ClinicalTrials.gov records with yesterday's and sends you the differences: status, dates, enrollment, endpoints, sites, and the reason a trial stopped.
Free plan is free for good: one sponsor, one disease, no card. Paid plans from $49/month.
From the sweep of 28 August 2026739 changes on 357 trials
2026-08-27
critical
Trial terminated
Trial terminated: Stopped for futility.
Primary completion moved earlier: 2027-12 → 2026-06-24
Completion moved earlier: 2027-12 → 2026-06-24
Trial terminated: Stopped for futility.
Primary completion moved earlier: 2027-12 → 2026-06-24
Completion moved earlier: 2027-12 → 2026-06-24
2026-08-22
critical
Reclassified as terminated (was completed)
Trial terminated: Trial was rendered as cancelled work ongoing in the book of business.
Trial terminated: Trial was rendered as cancelled work ongoing in the book of business.
2026-08-27
notable
Primary completion pushed: 2029-02-13 → 2029-06-04
Completion pushed: 2029-12-20 → 2030-06-06
Completion pushed: 2029-12-20 → 2030-06-06
2026-08-27
notable
Primary completion pushed: 2026-07 → 2027-01
Completion pushed: 2026-08 → 2027-02
Completion pushed: 2026-08 → 2027-02
2026-08-28
critical
Primary completion pushed: 2026-04 → 2027-08
2026-08-28
notable
Primary completion pushed: 2026-09-18 → 2027-02-17
Six real entries from the seven days to 28 August 2026, exactly as detected. Every value is checkable on ClinicalTrials.gov by NCT number.
ClinicalTrials.gov keeps every version. Nobody has time to read them.
A registry record can change quietly: a completion date slides a year, an endpoint is reworded, a stopped trial gets its reason weeks later. The registry stores each version but shows you one trial at a time. DataLookout reads the versions for the sponsors and diseases you name and reports only what differs, with the old value next to the new one.
- Overall statusrecruiting, suspended, terminated, completedThe change most people want first. Terminations and suspensions are marked critical.
- Primary completion dateand study completion dateThe readout clock. A push of 30 days or more is flagged; the size of the shift is shown as a floor.
- Enrollment countCuts often precede a termination. Increases usually mean an expansion.
- Why the trial stoppedfree text from the sponsorQuoted verbatim, because it typically arrives after the status flips.
- Primary endpointsRewrites are flagged, not interpreted. You read the before and after.
- Phase, arms, sites, sponsorand new trials registeredPhase moves, arm and site counts, a change of lead sponsor, and any new record from a sponsor you watch or in a disease you watch.
Trials at Risk
The ones slipping while still marked "Recruiting."
A trial rarely announces trouble. It pushes its date, trims enrollment, and rewrites an endpoint, each edit small enough to pass. Trials at Risk collects those signals across your watchlist and ranks the trials that show more than one.
Full list on Starter and Pro. Free shows the top trial.
2026-08-15
notable
Primary completion pushed 27 months: 2029-01-23→2031-04-30
2026-08-15
minor
Primary endpoints rewritten in the same update
2026-08-15
minor
Enrollment raised 470→580
2026-08-15
minor
Status unchanged: Recruiting
Three signals in one registry update, detected 15 August 2026. Still recruiting on the record.
How it works
Three steps, then it runs without you. Everything is drawn from ClinicalTrials.gov's official API, unmodified.
- Name a sponsor or diseaseSearch 150,000+ trials by sponsor, condition, or NCT number. Add what matters to your watchlist, or save any search (a phase, a status, a start-date window) and get alerts when its results change.
- We compare, every morningEach watched record is diffed against yesterday's version across the fields above. Changes are graded critical, notable, or minor.
- You read the differencesA daily or weekly email covering your watchlist and saved searches, plus a dashboard where each change can be marked read or done, with the change history, a landscape view of every sponsor active in a disease, and Trials at Risk.
Pricing
Start free, no card. Move up when you need more sponsors, more diseases, more saved searches, more tracked trials, or the full at-risk list. Cancel from your account page.
| Free$0 foreverone sponsor, one disease | Starter$49 / monthanalysts, BD, research sites | Pro$149 / monthteams tracking a field | |
|---|---|---|---|
| Watchlist | 1 sponsor + 1 disease | 3 sponsors + 3 diseases | Unlimited |
| Saved searches with email alerts | 1 | 3 | Unlimited |
| Tracked individual trials | 5 | 25 | Unlimited |
| Daily change detection | Yes | Yes | Yes |
| Email digest (watchlist + saved searches) | Daily or weekly | Daily or weekly | Daily or weekly |
| Trials at Risk | Top trial only | Full list | Full list |
| Landscape reports | Preview | Full | Full |
| Weekly report | Top 3 changes | Full | Full |
| Pipeline Pulse | Yes | Yes | Yes |
| CSV export | — | — | Yes |
| Support | — | Priority email | |
| Start free | Start free, upgrade inside | Start free, upgrade inside |
Search and browse 150,000+ trials on every plan. Prices in USD, billed monthly through Stripe.
FAQ
Frequently asked questions
Is the free plan really free?
Yes. The free plan is free forever. You get 1 sponsor and 1 disease watchlist with full change detection, and you can search and browse 150,000+ trials with no time limit. Upgrade to Starter or Pro when you need more.
How is this different from searching ClinicalTrials.gov directly?
ClinicalTrials.gov keeps a full version history for every trial and offers RSS feeds for new and updated studies. What it does not do is compare versions across a set of sponsors or diseases and tell you which field moved and from what value. DataLookout does that comparison for your watchlist every morning.
What is change detection?
DataLookout takes daily snapshots of the trials it tracks and compares twelve fields on each one. When a trial changes status, advances phase, updates enrollment, moves a completion date, modifies a primary endpoint, changes its interventions, adds sites, gains a stated reason for stopping, or publishes its results, the change is recorded with the old and new value and graded critical, notable, or minor.
What is Trials at Risk?
Trials at Risk flags the active trials on your watchlist showing warning signs: a primary completion date pushed out by 30 or more days, enrollment cut, or a primary endpoint changed. Trials with several signals rank highest. Free accounts see the top trial; Starter and Pro see the full list.
Will I be notified about new trials, not just changes?
Yes. When a sponsor on your watchlist registers a new trial on ClinicalTrials.gov, or a new sponsor appears in a disease you watch, it appears in your next email digest as a New Trial entry, separate from changes to existing trials.
What are Landscape Reports and Pipeline Pulse?
A Landscape Report is a full breakdown of a disease area: every active sponsor grouped by phase, a phase distribution chart, recent protocol changes, and new entrants. Pipeline Pulse ranks 86 disease areas by trial momentum, a composite of Phase 3 density, new starts, and new sponsor entrants.
Name one sponsor or disease. Read tomorrow's differences.
Free forever for one of each. No card.