Incyte Clinical Trial Pipeline — 49 Active Studies

Monitor Incyte's clinical trial pipeline in real time. Daily alerts for new trial registrations and status changes across all therapeutic areas and phases.

Track Incyte Pipeline — Free

Incyte pipeline at a glance (March 2026)

49
Active Trials
27
Currently Recruiting
Phase 1: 14 Phase 2: 17 Phase 3: 15 Other: 3

About the Incyte clinical program

Incyte has built a focused clinical portfolio around kinase inhibition — JAK, FGFR, and IDH — with growing programs in checkpoint inhibition and CSF1R-targeted therapy. Jakafi (ruxolitinib), the first JAK1/2 inhibitor approved, remains central across myelofibrosis, polycythemia vera, and acute/chronic graft-versus-host disease. Opzelura (ruxolitinib cream) extends the JAK franchise into dermatology — approved for atopic dermatitis and vitiligo, with ongoing trials in additional inflammatory skin conditions. Pemazyre (pemigatinib) pioneered FGFR inhibition in cholangiocarcinoma and myeloid/lymphoid neoplasms with FGFR1 rearrangements. Zynyz (retifanlimab), their PD-1 inhibitor, is approved in Merkel cell carcinoma and anal canal carcinoma, with expansion trials ongoing. Niktimvo (axatilimab), targeting CSF1R in chronic GvHD, represents a new mechanism in allogeneic transplant complications.

Key therapeutic areas

Key pipeline programs

Monitor the Incyte pipeline daily

Get alerts when Incyte registers new trials or updates existing protocols. Free 14-day trial — no credit card required.

Start Monitoring Free

Top Incyte trial indications

Condition / IndicationTrials
["Myeloproliferative Neoplasms"]5
["Hidradenitis Suppurativa (HS)"]5
["Chronic Graft-versus-host-disease"]5
["Solid Tumors"]3
["Hidradenitis Suppurativa"]3
["Healthy Participants"]3
["Prurigo Nodularis"]2
["Ovarian Cancer"]2

Why monitor Incyte's clinical trial activity

Incyte's JAK inhibitor expansion — particularly Jakafi combinations in myelofibrosis (with BCL-2, BET inhibitors) and Opzelura label expansions in dermatology — generates consistent new trial registrations. Their FGFR inhibitor portfolio (pemigatinib, futibatinib partnership) is closely tracked in cholangiocarcinoma and urothelial cancer by oncology BD teams.

DataLookout monitors ClinicalTrials.gov daily and surfaces changes to Incyte's registered studies — new trial registrations, status transitions (e.g., "Not yet recruiting" → "Recruiting"), site additions, and protocol amendments. This is the intelligence layer that bridges the gap between quarterly investor calls and real-time pipeline developments.

How DataLookout tracks Incyte trials

Automate your Incyte pipeline intelligence

Used by pharma BD, strategy, and competitive intelligence professionals. Setup takes under 5 minutes.

Start Free Trial

Frequently asked questions

What is Incyte's focus in hematology clinical trials?

Incyte's hematology pipeline is anchored by Jakafi (ruxolitinib) — with ongoing trials in myelofibrosis combination regimens (adding BCL-2 inhibitors, BET inhibitors, and PI3K inhibitors), polycythemia vera, and GvHD. Niktimvo (axatilimab), approved for chronic GvHD, represents a new mechanism extending into other fibrotic and inflammatory allograft complications.

How many Incyte trials are currently recruiting?

Based on current ClinicalTrials.gov data, 27 Incyte-sponsored trials are actively recruiting patients across hematology, oncology, and dermatology programs.

Can DataLookout alert me to new Incyte dermatology trials?

Yes. You can create a watchlist combining Incyte as the sponsor with dermatology indication keywords — atopic dermatitis, vitiligo, alopecia areata. DataLookout will deliver daily alerts when new Incyte trials matching those criteria are registered or when existing trial statuses change.

Track other major pharma pipelines